MGF – Research-Grade Mechano Growth Factor Peptide

MGF (Mechano Growth Factor) is a synthetic splice variant of insulin-like growth factor 1 (IGF-1Ec), characterized by a distinct 24-amino-acid C-terminal E-domain extension that separates it structurally from systemic IGF-1 and from the extended analog PEG-MGF. As a locally acting splice-variant peptide, MGF is utilized in laboratory research settings as a reference material for studying alternative splicing products of the IGF-1 gene, E-domain receptor-independent signaling models, and structure–activity relationships within the growth factor peptide class.

Owing to its defined sequence and short in-solution half-life relative to PEGylated analogs, MGF exhibits physicochemical properties that allow researchers to examine peptide stability, transient signaling kinetics, and putative regulatory activity in vitro without reliance on full-length native growth factor proteins. Its reproducible synthetic profile supports controlled use in mechanistic assays, comparative splice-variant studies, and exploratory biochemical research conducted under controlled laboratory conditions. This material is intended strictly for laboratory research use only and is not designed for human or veterinary application.