ACE-031

ACE-031 – Research-Grade Recombinant Fusion Protein

ACE-031 is a recombinant fusion protein composed of the extracellular domain of Activin Receptor Type IIB (ActRIIB) linked to the Fc region of human IgG1. This engineered construct forms a disulfide-linked dimer and is structurally distinct from short synthetic peptides or full-length endogenous receptors.

In laboratory research settings, ACE-031 is utilized as a reference material for studying ligand–receptor interaction models, extracellular domain binding dynamics, and structure–function relationships within TGF-β superfamily signaling pathways. The fusion design enables controlled investigation of receptor-domain behavior in vitro.

Unlike small peptide constructs, ACE-031 represents a higher-order biologic system that may exhibit domain-level folding and post-translational modification depending on expression conditions. This material is intended strictly for laboratory research use only and is not designed for human or veterinary application.